Image brain activity like never before

fUSI is among the most versatile technologies to image brain activity at high spatiotemporal resolution, with a large field of view and in-depth. The fUSi technology is developed for broad neuroscience preclinical and clinical research. The AUTC fUSI scanner offers a wide range of qualitative and quantitive measurement, including:

  • Cerebral Blood Volume (Power Doppler) that relates to neural activity

  • Cerebral Blood Flow and perfusion with quantitative RBCs velocity measurement (only in the cortex) with color coded flow orientation (Color Doppler)

  • Microvascular anatomy including automated segmentation and registration of brain vasculature on the standard Atlas (available for rodents, marmosets, NHP)

  • Brain tissue echogenicity (B-mode) for live imaging of brain tissue and neuronavigation. This mode includes direct observation of brain infarct, tumors, hemorrhage. It is also used for image-guided intracranial injections and in vivo delivery of drugs, stem cells, or other agents.


Large-scale brain circuit imaging

fUSI is a unique technology for decoding brain activity at mesoscopic scale offering unprecedented spatio-temporal resolution (100µm/100ms), large field of view (several cm) and depth of field (up to 6.5cm). fUSi does not require contrast agent and can be used in a large variety of animal models including rodents, non-human primates and even birds.

Costless alternative to fMRI to study brain pathologies

Get rid of the confounding effects of anesthetics

The fUSi technology allows both measurement of brain activity and blood flow in awake and chronic conditions. fUSI is efficient to track changes over time in various pathologies, including stroke, traumatic brain injury, vascular cognitive impairment (AD, PTSD, TBI), and more.

More accurate than in vitro research

Nowadays it is impossible to mimic the entire brain in a dish. fUSI is suited for a wide range of applications, including in vivo pharmacology studies. Visualize the effects of your active compound directly in the brain using functional activity, resting-state or dynamic connectivity mapping.

Full compatibility with electrophysiology and a wide range of techniques

fUSi is compatible with a large variety of technologies for the study of brain activity including 2-photons laser-scanning microscopy, electrophysiology with flex-polyimide and silicon probes, optogenetics, pharmacogenetics and more…

Clinical research

fUSI is a versatile technology for imaging brain perfusion and activity non invasively in neonates and adults for image-guided procedures

6 to 20 MHz
80 to 250 µm
100 ms
1 to 3 cm
1 to 6 cm

Latest Publications

This section presents the recent scientific publications and news using the fUSI technology

Read latest fUSi publications

“fUSI is a breakthrough technology for real-time imaging of brain circuits dynamics at mesoscale for fundamental research and in clinics”


Our clients

We aim to expand the fUSI technology, and we are currently collaborating with a network of scientists in academia, clinics, and industry located in Europe and abroad (EU, UK, USA, Asia). Our collaborative “fUSI community” comprises more than 30 principal investigators worldwide, and hundreds of users have already acknowledged the versatility and reliability of AUTC fUSI solutions. Contact us to know more and discover how fUSI can help you to reach your research objectives.

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